I want to pass this along to the people who are seeing hordes of people coming through and chasing Pokemon. If you want to remove your location or your business from this app you can go to the support page, they don't really advertise this you can do this without logging in and may have to put in your google account credentials, but you will be able to go in and you will see a report an issue with a gym or a poke@stop. Click this and you will want to put in a gym removal request or a business removal request. In the drop down bar for removal, it does not have an option for removal, so you will have to write in this request. The closest thing to this will be the dangerous stop or gym option. You might not know the gym name for your business because they have them listed as gyms instead of businesses but you want to put in your business name and put in the exact coordinates of your location.
This can help the support team locate you quicker and once you do all this you submit the form and hope they take quick action. This is not a guarantee that this is going to remove your location from one of these poke@stopes, but it's better than nothing. You can do this weekly go in and check in and keep requesting. This is an option to get in and keep your location from being invaded.