Acro–dermato–ungual–lacrimal–tooth (ADULT) syndrome is a rare genetic disease.[1] ADULT syndrome is an autosomal dominant form of ectodermal dysplasia, a group of disorders that affects the hair, teeth, nails, sweat glands, and extremities.[2] The syndrome arises from a mutation in the TP63 gene.[3] This disease was previously thought to be a form of ectrodactyly–ectodermal dysplasia–cleft syndrome (EEC), but was classified as a different disease in 1993 by Propping and Zerres.