Today a lady patient came to my chamber. She came to check her lipid profile. On enquiry, she mentioned that she had a previous history of dyslipidemia and at a certain stage she took lipid-lowering drugs for a few months; later stopped. Today she wanted to check the current lipid status in her blood.
I ordered the lipid profile. When the report came, it was shown that her total cholesterol and LDL were quite high; 8.4 mmol/L and 5.7 mmol/l respectively.
I advised her to start lipid-lowering drugs again along with dietary control and daily physical exercise. I gave her atorvastatin 10 mg daily once, at night time. I told her to for follow up in 2-3 months.
In relation with this post, we should keep some adverse effects of statin group drugs in our mind which is the main lipid-lowering drugs in the market. Myopathy is the main side effect of stains occurring in up to 5% of the patients treated with these drugs. Muscle pain (myalgia) is a prominent symptom. A deranged liver function is also seen following startling of statins.
Statins type of lipid-lowering drugs should be taken at night, preferably as the last thing because this is the time when the majority of cholesterol synthesis takes place.
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