Some of my favorites coming into this year would be Iota, Substratum, Powr Ledger and Oyster Pearl. I feel all these projects have real world applications and have some unique ways of using blockchain technology. Iota long term (2-5 years depending on developement) I think will be a big winner, with the others all gearing up to have solid years in their own regards with projects coming out in Q1 and Q2.