Based on the results of the observation on the disease of the leaf nodule (Procontarinia matteiana) affected by leaf bleeding, the symptoms seen on the leaves of the guava are uneven or swollen lumps of young leaves in the form of nodules (there are larvae of Procontarinia leaf fly matteiana in the leaf nodule). Large cashew nodule disease is included in the hyperplastic symptom type caused by leaf fly (Procontarinia matteiana). According to Novitasari (2011), the symptom of nodule leaf attack is to attack vegetatively grown plants (in young leaves), if severe attack will cause the leaves to roll, then the symptoms are so obvious as a result of pink nodule leaf disease is the emergence rash on the leaves, when palpable leaf feels rough. If a nodule is slashed using a razor blade will be found a maggot or a small larva of Procontarinia matteiana flies carrying a virus from a woody gell virus