A few years ago I found a paper that tried to calculate what is the most remote part of Europe, by taking the area (+-10 km or so) from the roads.

It was incredible how small the oases for the wildlife are.
And after the fragmentation of the habitats, it's the one-way street for the extinction.

It would be interesting to see the speciation and diversification of Cats, Dogs, Rodents and Pidgeons during the next 10 million years...
(*sarcasm)