Binance is the only centralised exchange which I trust right now, I mean it's not absolutely impossible to hack. But Binance is continuously improving their security infrastructure and have low track record of any significant breach. Plus they are situated in Hong Kong, China, so they have the privelage to stand up to US regulations and the corrupt hands of my shithole country's (India) socialist government. Even though Zhao had to move to Tokyo due to some regulations by the Chinese government. But the fact that it contineus to be the top cryptocurrency exchange in not only China but also Asia gives me confidence that they are not going anywhere. They will soon lauch the Korean language version of their website. Fun fact, Korean is the only language isolate which is the national language of a country.
I was was recently watching Binance CEO Zhao ChengPeng's talk at Bitcoin Revolution Conference, 2018 on the Boxmining channel and his remarks on decentralised exchanges not being able to handle Binance's volume is pretty realistic.
Binance exchange also supports the most number of cryptocurrencies and I think it is the only place where you can trade IOTA currently. I may be wrong but Binance will still be more efficient platform for trading IOTA.
Now, I'm not a Binance fanatic and nor am I being paid by them. In fact, I'm not big enough to be paid by anyone to do anything. But the truth is that Binance is standing above most of its' competition with decent customer service, a good UI, lots of features and coins and and an ever increasing user-base. I mean its' users are constantly increasing even after a temporary ban of new registrations due to website maintenance.
Even Coinbase now has more registered members than the brokerage firm Schwab ( full story ) . Moreover Binance is now forcing its' competitors like Coinbase to improve its service and treat their customers more nicely. Although I still see posts on cryptocurrency subreddits about how various exchanges like bittrex are holding their funds hostage.
So my final advice is always to store offline and use Binance as your main Cryptocurrency exchange. FOR NOW