Some women even in the 50-year-old can be successful pregnancy, but some women are 30 years old when they can not be pregnant, and recently, from the University of Gothenburg scientists on this phenomenon were analyzed, one of the factors that are women The beginning of menopause will be affected by the release of its body's egg cells, the relevant research published in the International Journal Current Biology.
The researchers then opened the biological clock to control the fertility of women, as newborns need nutrients to survive the same, the uterus of the egg cells also need from the primary follicular granules of nutritional supplements, the researchers found in the granulosa cells A signal pathway may allow immature egg cells to survive.
The mTOR signaling pathway in granulocytes is essential for the activation of receptor ligand growth factors, and the receptor ligand growth factor can then bind to the c-kit receptors in the egg cells to determine the fate of the egg cells. Researchers Liu said that this mechanism can make granulocytes determine when the egg cells began to grow and when to death, from this level sense, the granular cells will provide a biological clock for the egg cells to monitor the occurrence of female menopause.
Researchers believe that this study can be used to stimulate the way to stimulate the growth of egg cells can not mature, and later researchers can use this mechanism to control the development of human egg cells, the development of new therapy to treat clinical infertility.