By a News Reporter-Staff News Editor at Clinical Trials Week -- Fresh data on Fetal Distress are presented in a new report. According to news reporting originating from Zhengzhou, People’s Republic of China, by NewsRx correspondents, research stated, “The study aimed to explore the effects of maternal iodine status and thyroid diseases on adverse pregnancy outcomes. A prospective study was conducted on 2347 pregnant women, who provided 2347 urinary samples tested for iodine, 1082 serum samples tested for thyroid function, and 2347 questionnaires about demographic information.”
Our news editors obtained a quote from the research, “Their pregnancy outcomes were recorded and compared between different urinary iodine concentration (UIC) and thyroid function groups. Pregnant women with UIC between 150 and 249 mu g/L had lower incidences of preeclampsia (adjusted odds ratio (OR) 0.12, 95% CI: 0.01-0.87), placenta previa (adjusted OR 0.06, 95% CI: 0.01-0.69) and fetal distress (adjusted OR 0.10, 95% CI: 0.02-0.64) than the reference group (UIC < 50 mu g/L). Women with UIC between 100 and 149 mu g/L had lower risks of abnormal amniotic fluid (adjusted OR 0.32, 95% CI: 0.12-0.87) and fetal distress (adjusted OR 0.08, 95% CI: 0.01-0.82). Women with UIC above 249 mu g/L. had a significant higher rate of abnormal amniotic fluid (adjusted OR 0.38, 95% CI: 0.16-0.89). Clinical and subclinical hypothyroidism during pregnancy increased the risk of preterm delivery by 4.4 times (P = 0.009) and 3.0 times (P = 0.014), respectively. Isolated hypothyroxinemia had increased odds of having macrosomia (adjusted OR 2.22, 95% CI: 1.13-4.85). Clinical hyperthyroidism was significantly associated with miscarriage (adjusted OR 2.12, 95% CI: 1.92-96.67) and fetal distress (adjusted OR 9.53, 95% CI: 1.05-81.81). Subclinical hyperthyroidism had a significant association with umbilical cord entanglement (adjusted OR 3.82, 95% CI: 1.38-10.58). Isolated hyperthyroxinemia was associated with preterm delivery (adjusted OR 4.73, 95% CI: 1.49-15.05).”
According to the news editors, the research concluded: “Maternal iodine status and thyroid diseases during pregnancy were associated with adverse pregnancy outcomes.”
For more information on this research see: Associations of maternal iodine status and thyroid function with adverse pregnancy outcomes in Henan Province of China. Journal of Trace Elements in Medicine and Biology , 2018;47():104-110. Journal of Trace Elements in Medicine and Biology can be contacted at: Elsevier Gmbh, Urban & Fischer Verlag, Office Jena, P O Box 100537, 07705 Jena, Germany. (Elsevier - www.elsevier.com; Journal of Trace Elements in Medicine and Biology - http://www.journals.elsevier.com/journal-of-trace-elements-in-medicine-and-biology/)
The news editors report that additional information may be obtained by contacting J. Yang, Henan Prov Center Dis Control & Prevent, Dept. of Endem Dis Control & Prevent, Zhengzhou, Henan, People’s Republic of China. Additional authors for this research include Y. Liu, H.J. Liu, H.M. Zheng, X.F. Li, L. Zhu and Z. Wang.
The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.jtemb.2018.01.013. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.
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CITATION: (2018-04-30), Findings on Fetal Distress Discussed by J. Yang and Co-Researchers (Associations of maternal iodine status and thyroid function with adverse pregnancy outcomes in Henan Province of China), Clinical Trials Week, 415, ISSN: 1543-6764, BUTTER® ID: 015596918
From the newsletter Clinical Trials Week.
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