By a News Reporter-Staff News Editor at Diabetes Week -- Data detailed on Nutritional and Metabolic Diseases and Conditions - Type 2 Diabetes have been presented. According to news reporting originating in Heilongjiang, People’s Republic of China, by NewsRx journalists, research stated, “Experimental evidence suggests saturated fatty acids (SFAs) are associated with insulin resistance, but results from epidemiological studies on fasting SFAs-diabetes risk are inconsistent. We investigated SFA (fasting and 2-hour postprandial) profiles and diabetes risk.”
The news reporters obtained a quote from the research from Harbin Medical University, “Setting: A total of 8940 participants were recruited for the Harbin People’s Health Study in 2008. Serum SFAs (fasting and 2-hour postprandial) at baseline in Chinese men and women without diabetes were profiled, and type 2 diabetes was ascertained using World Health Organization criteria after 4 to 7 years of follow-up. Associations between 2-hour postprandial SFA (2h-SFA) and diabetes. At baseline, incident cases of diabetes were older with a higher body mass index and waist circumference. After a mean follow-up of 6.7 years, 658 incident cases of diabetes occurred. After propensity score computation and inverse probability of treatment weighting (IPTW) estimation, fasting SFAs were unrelated to diabetes risk but IPTW-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the highest tertile of 2-hour postprandial stearic acid (2h-SA), 2hour postprandial palmitic acid (2h-PA), and 2h-SFA for diabetes risk were 2.50 (2.08 to 3.16), 1.56 (1.23 to 2.02), and 1.70 (1.34 to 2.17), respectively (P-trend, 0.0001). Similarly, 2h-SA/fasting SA, 2hPA/fasting PA, and 2h-SFA/fasting SFA ratios [IPTW-adjusted OR (95% CI): 2.94 (2.39 to 3.58), 2.31 (1.80 to 2.93), and 2.42 (1.91 to 3.11), respectively; P-trend, 0.0001] predicted the diabetes risk.”
According to the news reporters, the research concluded: “Higher serum 2h-SFA (but not fasting SFA) independently predicted diabetes risk.”
For more information on this research see: Postprandial Saturated Fatty Acids Increase the Risk of Type 2 Diabetes: A Cohort Study in a Chinese Population. Journal of Clinical Endocrinology & Metabolism , 2018;103(4):1438-1446. Journal of Clinical Endocrinology & Metabolism can be contacted at: Oxford Univ Press Inc, Journals Dept, 2001 Evans Rd, Cary, NC 27513, USA. (The Endocrine Society - http://www.endo-society.org/; Journal of Clinical Endocrinology & Metabolism - http://jcem.endojournals.org/)
Our news correspondents report that additional information may be obtained by contacting Y. Li, Harbin Med Univ, Sch Public Hlth, Dept. of Nutr & Food Hyg, Natl Key Discipline Lab, Harbin 150081, Heilongjiang, People’s Republic of China. Additional authors for this research include X. Meng, X.R. Deng, A.P. Okekunle, P. Wang, Q. Zhang, L.Y. Ding, X.X. Guo, M.F. Lv, C.H. Sun and Y.J. Wang.
The direct object identifier (DOI) for that additional information is: https://doi.org/10.1210/jc.2017-01904. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.
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CITATION: (2018-04-30), Investigators from Harbin Medical University Zero in on Type 2 Diabetes (Postprandial Saturated Fatty Acids Increase the Risk of Type 2 Diabetes: A Cohort Study in a Chinese Population), Diabetes Week, 193, ISSN: 1537-1433, BUTTER® ID: 015597165
From the newsletter Diabetes Week.
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