No. The Great Tribulation doesn't start until after the antichrist signs a 7 year peace agreement with Israel.

(Daniel 9:27 NIV) He will confirm a covenant with many for one 'seven.' In the middle of the 'seven' he will put an end to sacrifice and offering. And on a wing of the temple he will set up an abomination that causes desolation, until the end that is decreed is poured out on him."