I was recently asked this question in an interview and thought I'd share the clip here (click on image above).
I believe it doesn't matter how much money you have - whether it's $100 or $100,000 - what's important is to invest only in projects that you understand and believe in. Also, I would not put all my money into one thing, but in a few different ones (--> diversification = not putting all your eggs in one basket)
I would spread my investment over about 5 projects - some solid ones that have been around for a while (not that that's any guarantee...) and one or two inexpensive ones, which you find highly promising. While you will only get a fraction of a coin with the bigger ones like Bitcoin, you might get hundreds or even thousands of coins for a few Dollars, of new, promising projects.
I also share my 5 favorites in this interview.
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