In almost all initiatory clinical trials, years 0-2 are where most of the findings are made in regards to risk, adverse events, etc...
Most drugs don't need lengthy and costly (and potentially deadly via restricting the prevention method/cure from the high risk/sick) 15 year clinical trials like the FDA and government regulations try to force on everyone today.
Years 2-15 are statistically when the fewest new findings are made for any new vaccine or drug.
Regulatory capture systems know that one of the best ways to kill competition is to make the hoops so large, that small competitors can't jump through them.
The biggest pharma companies realize that increasing costs for clinical trials (primarily through lobbying for extended testing phases, in some cases up to and over 15 years) makes it so smaller competitors can't compete.
If you want to get rid of govt's regulatory capture, one of the best ways is to allow the market to determine the actual turnaround time for vaccine and medicine clinical trials, through multiple quality private testing companies that have to protect their reputation for decades and centuries to come, unlike protected bureaus like the FDA today.
In a free market most vaccines and medicines could be approved within a year or 2, safely, and the suffer and death caused at the hands of government's regulatory capture system which needlessly extends clinical testing would be abolished in favor of freedom and shorter trial testing periods.
The smallest pharmaceutical competitors would finally be able to compete with the largest firms in that case and we'd have less suffering and death that today is caused at the hands of government regulations such as needless 15-year clinical trials when we know vaccines and drugs are safe after 1 or 2 years.
I can remember when real libertarians used to fight against the lengthy FDA timeline regulations, now half of them (the conspiratorial type usually) are all for more statism and longer testing cycles that are often unneeded and sadly harmful/deadly.