I'm afraid I'm not sure what you are getting at; being in a virtual world isn't intended to distort reality; it is to take you to a completely different reality. The therapeutic example I gave doesn't have that intention either (to distort reality itself).

I took my VR headset (Oculus DK1) on a vacation where I visited friends who are practicing psychologists. They are not technically inclined. I let them give it a try and they stated that this would work wonders with some of their patients because, as they put it, they really felt like they were somewhere else, in environments that would be very therapeutic to them.