A team of researchers from Cleveland Clinic, Louis Stokes Cleveland VA Medical Center, Kaiser Permanente Northwest, and other clinical sites have demonstrated that a new blood test known as IsoPSA detects prostate cancer more precisely than current tests in two crucial measures – distinguishing cancer from benign conditions, and identifying patients with high-risk disease.
“Despite criticism, PSA has transformed the landscape of early detection, screening, and management of prostate cancer in the last few decades,” said Dr. Klein, chair of Cleveland Clinic’s Glickman Urological & Kidney Institute. “Unfortunately, PSA is tissue-specific but not cancer-specific, leading to overdiagnosis and overtreatment of biologically insignificant cancers, which is widely recognized as a key limitation in its clinical utility.”
What is PSA ? - Prostate-specific antigen, or PSA, is a protein produced by cells of the prostate gland.
The new tests can reduce unnecessary biopsies by almost 50%.
Mark Stovsky, M.D., co-author and staff member, Cleveland Clinic Glickman Urological & Kidney Institute. said -
“Due to its inherent simplicity, requiring only a blood draw and presenting information to the physician in familiar context using a single number – just like PSA itself – we are quite hopeful in IsoPSA’s future utility after further validation studies,”
What is the normal PSA level?
There is no specific normal or abnormal level of PSA in the blood. In the past, most doctors considered PSA levels of 4.0 ng/mL and lower as normal. Therefore, if a man had a PSA level above 4.0 ng/mL, doctors would often recommend a prostate biopsy to determine whether prostate cancer was present.
What does it mean when your prostate levels are high?
Thirteen per cent of men over 55 have a PSA level of ≥ 4 ng/ml but this does not automatically mean you have cancer. An elevated level can also be due to other conditions, such as benign enlargement of the prostate (BPH), a urinary tract infection or a prostate infection.
What is a 4k blood test?
The 4Kscore® Test (OPKO Lab, Nashville, TN) is a new blood test that accurately identifies the risk of aggressive prostate cancer; it plays an important clinical role as a reflex test prior to proceeding with initial prostate biopsy in men with an elevated PSA level or abnormal digital rectal examination results
What not to eat when you have prostate cancer?
Diet Tips for Prostate Health
•Eat Fruits and Vegetables. ...
•Limit Consumption of Animal Protein. ...
•Seek Plant Protein. ...
•Green Tea. ...
•Whole Grains. ...
•Limit Sugary Drinks. ...
•Choose Organic Foods when Possible
Foods to avoid
•Red Meat. You may love your steak but the problem with meat is that it elevates levels of arachidonic acid in your body, and that, in turn, increases inflammation, the very thing your enlarged prostate does not need. ...
•Eggs & Poultry. ...
•Processed foods & sugar. ...
•Caffeine. ...
•Spicy foods. ...
•Dairy. ...
•Alcohol
More about dietary details will be continued ....
Reference - https://newsroom.clevelandclinic.org
https://www.cancer.gov/types/prostate/psa-fact-sheet
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444768/
www.prostatecancer-riskcalculator.com/psa-test