Effects of Treatment of Metabolic Acidosis in CKD

This article is a systematic review and meta-analysis which evaluates the effects of using oral alkali supplementation in patients with chronic kidney disease (CKD) and metabolic acidosis. It seems that there is a trend towards a reduction in the rate of progression to end stage renal disease (ESRD)

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Navaneethan, Sankar, Jun Shao, Jerry Buysse and David A. Bushinsky. “Effects of Treatment of Metabolic Acidosis in CKD." Clinical Journal of the American Society of Nephrology 14, no. 7 (2019): 1011-1020. doi: https://doi.org/10.2215/CJN.10791016