This post is showing the sodium transport coupled with the transport of dicarboxylates in the apical and basolateral membranes of the S1 segment of the proximal tubule.
- The Na/K ATPase, which brings 2 potassium ions into the cell and releases 3 sodium ions into the interstitial space.
- The sodium/dicarboxylate cotransporter (NaDC1) at the apical membrane, which brings in 3 sodium ions from the filtrate together with 1 dicarboxylate ion which could be citrate, α keto-glutarate or succinate.
- The sodium/dicarboxylate cotransporter (NaDC3) at the basolateral membrane, which brings in 3 sodium ions from the interstitium and brings in mainly α keto-glutarate. This transporter is important for the organic anion transport which will be shown at a later post
