Molecular weight: 1046
Formula: C50H71N13O12
Angiotensin II is an 8 amino acid peptide formed after the cleaving of 2 amino acids from angiotensin I by the angiotensin converting enzyme (ACE) which exists mainly in the lungs. Angiotensin II is a powerful vasoconstrictor and promotes the secretion of vasopressin in the CNS and aldosterone in the adrenal gland. In addition, it increases the activity of the NHE3 exchanger in the proximal tubule. It acts as a hormone. It actes through 2 receptors, the AT1 and AT2. AT1 mediates most of the effects mentioned above
