Serious hypotension (low blood pressure) can result if you combine dermaroller with topical Minoxidil. To anyone reading, please be very careful combining these two methods. A solution to avoid the hypotension that I recommend would be to skip minoxidil application 24 hours before and after dermaroller application. The stimulation from the dermaroller can induce wound healing and regeneration but also magnify the hypotensive(low blood pressure) side effect of Minoxidil. Please be careful.