Hive is weird because of the account and key setup. With this, you could change your owner key to one that is on the ledger so you never have to expose it on a computer.
However, you may want to use your posting key a lot so that key could be a bit less secure and stored on your computer or mobile phone.
A lot of different ways to use the ledger but that creativity will be left up to app developers and users.
RE: Hive Application for the Ledger Nano S/X Hardware Wallet