Hello everyone, how are you all? Hope you all are doing well and great i am too. Many people have dust allergy, allergy to some substances and some fragrances. I too have dust allergy. When i clean my room, then next day i will get fever, cold. Some people will get polyp in the nose and they will come to hospital with the complaints nasal block, allergy, cold and sneezing. So ENT doctor will do surgery for that polyp, they will remove that polyp and they will send the polypoidal tissue to histopathological examination to know which kind of polyp whether its inflammatory polyp, allergic polyp or any fungus is there in it bcz mucormycosis is commonly seen in the nasal area which got infected. This nasal polyp later we will gross and process it and finally we will get on slide. Then we will see under our microscope.

Microscopic findings

You can see the lining epithelium of the polyp is pseudostratified ciliated columnar epithelium. Yiu can see the cilia clearly. The subepithelium is polyp core shows dense inflammation and congested and dilated blood vessels.

The dense inflammatory infiltrates comprising of lymphocytes, plasma cells and eosinophils. Here we have to remember one thing that if more eosinophils are seen infact predominantly eosinophils then its allergic condition and we will give allergic nasal polyp as final impression. If we see more of lymphocytes and plasma cells than eosinophils then its inflammatory nasal polyp. So here in our case its Inflammatory nasal polyp.

The below images you can see are having edema in the stroma.

We have to search for fungal profiles also and we have to give negative impression at the end.

Hope you understood nasal polyp and why its important to examine pathologically. I will come with new one in my next post.

References

• Rosai and Ackerman's Surgical Pathology - 11th Edition

Thanks for reading,
With regards,