Since it has been very pleasant to write about terpenes, I decided that I will go a little deeper into the knowledge of this plant that we still know a lot about. little, and also talk about cannabinoids, the protagonists of this medicine.
What? Do you think talking about cannabinoids is talking about THC and CBD? So, click on this short list of SOME of the cannabinoids already studied:
Cannabidiol (CBD)
Cannabidiolic Acid (CBDA)
Cannabidiorcol (CBDC1)
Cannabidiol Monomethylether (CBDM)
Cannabidivarin (CBDV)
Cannabidivarinic Acid (CBDVA)
Tetrahydrocannabinol, (THC)
10-oxo-delta-6a-tetrahydrocannabinol, (OTHC)
Delta-8-tetrahydrocannabinolic acid, (Δ8-THCA)
Delta-8-tetrahydrocannabinol (d8THC, Δ8-THC)
Delta-9-tetrahydrocannabinol (d9THC, Δ9-THC, THCA)
Delta-9-tetrahydrocannabinol-C4 (THC-C4)
Delta-9-tetrahydrocannabinolic acid A (Δ9-THCA, THCA-A)
Delta-9-tetrahydrocannabinolic acid B (Δ9-THCB, THCA-B)
Delta-9-tetrahydrocannabiorolic acid, Δ9-THCA-C1, THCA-C1
Delta-9-tetrahydrocannabinolic acid C4, Δ9-THC-C4, THCA-C4
Delta-9-tetrahydrocannabiorcol (Δ9-THC-C1)
Delta-9-tetrahydrocannabivarin (THCV)
Delta-9tetrahydrocannabivarinic acid (THCVA)
TriHydroxy-delta-9-tetrahydrocannabinol (TRIOH-THC)
Cannabigerol (CBG)
Cannabigerolic Acid (CBGA)
Cannabigerolic Acid Monomethylether (CBGAM)
Cannabigerovarin (CBGV)
Cannabigerovarinic Acid (CBGVA)
Cannabigerol Monomethylether (CBGM)
Cannabinol (CBN)
Cannabinolic Acid (CBNA)
Cannabidiorcol (CBN-C1)
Cannabinol-C2 (CBN-C2)
Cannabinol-C4 (CBN-C4)
Cannabindiol (CBND)
Cannabinol Methylether (CBNM)
Delta-9-cis-tetrahydrocannabinol (CIS-THC)
Yes, and this is just a list of the most popular cannabinoids that have been studied or discovered, but we still don't know the total number of cannabinoids present in the plant. Needless to say, how much we still have to understand it, is it? Cannabis medicine is still in its infancy and I believe that in the future we will have each of these active ingredients isolated and studied in depth.
I have nothing to lose by researching each one of them and bringing this content here to you, without obligation. It will be a learning experience for me and for you. As I have the opportunity, I'll delve deeper into some (which alone already deserve a sequence of posts just for them). I'll try to get away from the obvious and I won't start the content from the CBD, but I still don't know which one will be chosen. If anyone out there has any suggestions, I accept!
But I can't finish this post without finally explaining: What are cannabinoids?
Well, cannabinoids are substances produced by animals and plants! In the case of us humans, we have endocannabinoids. Our body produces a channel for receiving these substances produced by ourselves, but which can receive external cannabinoids, in this case, the phytocannabinoids present in cannabis. All cannabinoids from plants are then classified as "phyto" because they are native to the plant kingdom. But its connections are PERFECT with our cannabinoid receptors.
Of the receptors in our body, the most famous and studied are the CB1 and CB2 receptors. Through these receptors come all the benefits, both neurological and physical (and of course, depending on the abuse, the collaterals). These receptors are in the whole body, not something "in the brain". They regulate mood, sleep, hunger, attention, etc. So, in summary:
By using external cannabinoids we are "supplementing" our "endocannabinoids", which will even be a theme for the future as well!
Thanks for your reading and attention. Thank you for your vote!
If you're interested in reading about terpenes, here are the ones I've already written:
Research sources for this article:
1, 2, 3 and 4
Thômas Helon Blum
PORTUGUÊS
Dado que tem sido muito agradável de escrever sobre os terpenos, decidi que vou me aprofundar um pouco mais no conhecimento dessa planta que ainda sabemos muito pouco, e falar também sobre os canabinoides, os protagonistas dessa medicina.
O que? Você acha que falar sobre canabinoides é falar de THC e CBD? Pois então, se liga nessa pequena lista de ALGUNS dos canabinoides já estudados:
Cannabidiol (CBD)
Cannabidiolic Acid (CBDA)
Cannabidiorcol (CBDC1)
Cannabidiol Monomethylether (CBDM)
Cannabidivarin (CBDV)
Cannabidivarinic Acid (CBDVA)
Tetrahydrocannabinol, (THC)
10-oxo-delta-6a-tetrahydrocannabinol, (OTHC)
Delta-8-tetrahydrocannabinolic acid, (Δ8-THCA)
Delta-8-tetrahydrocannabinol (d8THC, Δ8-THC)
Delta-9-tetrahydrocannabinol (d9THC, Δ9-THC, THCA)
Delta-9-tetrahydrocannabinol-C4 (THC-C4)
Delta-9-tetrahydrocannabinolic acid A (Δ9-THCA, THCA-A)
Delta-9-tetrahydrocannabinolic acid B (Δ9-THCB, THCA-B)
Delta-9-tetrahydrocannabiorolic acid, Δ9-THCA-C1, THCA-C1
Delta-9-tetrahydrocannabinolic acid C4, Δ9-THC-C4, THCA-C4
Delta-9-tetrahydrocannabiorcol (Δ9-THC-C1)
Delta-9-tetrahydrocannabivarin (THCV)
Delta-9tetrahydrocannabivarinic acid (THCVA)
TriHydroxy-delta-9-tetrahydrocannabinol (TRIOH-THC)
Cannabigerol (CBG)
Cannabigerolic Acid (CBGA)
Cannabigerolic Acid Monomethylether (CBGAM)
Cannabigerovarin (CBGV)
Cannabigerovarinic Acid (CBGVA)
Cannabigerol Monomethylether (CBGM)
Cannabinol (CBN)
Cannabinolic Acid (CBNA)
Cannabidiorcol (CBN-C1)
Cannabinol-C2 (CBN-C2)
Cannabinol-C4 (CBN-C4)
Cannabinodiol (CBND)
Cannabinol Methylether (CBNM)
Delta-9-cis-tetrahydrocannabinol (CIS-THC)
Pois é, e essa é só uma lista dos canabinoides mais populares e já estudados ou descobertos, mas ainda não sabemos o total de canabinoides presentes na planta. Não é preciso nem dizer o quanto ainda temos para compreendê-la não é? A medicina cannabica ainda está engatinhando e creio que num futuro teremos cada um desses princípio ativos isolados e estudados profundamente.
Eu não tenho nada a perder em pesquisar sobre cada um deles e trazer aqui pra vocês, sem compromisso, esse conteúdo. Será um aprendizado para mim e para vocês. Conforme eu tiver oportunidade, aprofundarei-me mais em alguns (que isoladamente já merecem uma sequência de posts só para eles). Vou tentar fugir do óbvio e não começarei o conteúdo pelo CBD, mas ainda não sei qual será o escolhido. Se alguém aí tiver alguma sugestão, eu aceito!
Mas não posso finalizar esse post sem afinal, explicar ao menos: O que são canabinoides?
Bom, canabinoides são substâncias produzidas por animais e por plantas! No caso de nós humanos, temos os endocanabinoides. Nosso corpo produz um canal de receptação dessas substâncias produzidas por nós mesmos, mas que podem receber canabinoides externos, no caso, os fitocanabinoides presentes na cannabis. Todos os canabinoides das plantas então são classificados como "fito" por serem naturais do reino vegetal. Mas suas ligações são PERFEITAS com os nossos receptores de canabinoides.
Dos receptores de nosso corpo, os mais famosos e já estudados são os receptores CB1 e CB2. Através destes receptores é que entram todos os benefícios tanto neurológicos como físicos (e claro, dependendo do abuso, os colaterais). Esses receptores estão no corpo inteiro, não é algo "no cérebro". Regulam humor, sono, fome, atenção, etc. Então, em resumo:
Ao utilizar canabinoides externos estamos "suplementando" os nossos "endocanabinoides", que inclusive serão um tema para o futuro também!
Obrigado pela sua leitura e atenção. Agradeço seu voto!
Se tiver interesse em ler sobre os terpenos, aqui estão os que eu já escrevi:
Fontes de pesquisa para esse artigo:
1, 2, 3 e 4