The current era in the middle east seems to be defined by the power struggle between US and Russia (and China seems to want to join in the mess with its one belt one road initiative), and between regional powers Saudi Arabia and Iran. That's one of the important dimensions of the Syrian conflict. It's not looking good for repairing US-middle-east relations. The young Arabs and other Middle-Easterners I've met, 99% of them hate the US government to the core (of course it does not follow that they hate Americans).