Iyi-Enu Mission Hospital since inception has been at the fore-front of missions and healing through tending the sick, the suffering and the dying.
It will be recalled that the Rev.Dobinson and Rev. F. N Eden under the church Missionary society (C. M. S) medical mission initiated what is today called "Iyi-Enu mission Hospital" when they saw the need to reach the people with medical services on their arrival at Ozalla, Onisha in 1890.
The Iyi-Enu mission Hospital of today started as a dispensary in a somewhat dilapidated mud building in old C. M. S compound which was originally built by the first Bishop on the Niger Territory - The Rt. Rev Samuel Ajayi Crowther - Who also who also lived there.
In 1913, the foundation stone of the new dispensary block, in memory of the late Ben. Henry Dobinson (the leader of the team) was laid by the Governor -General designate to Nigeria, Sir Frederick Lord Lugard. The late Dobinson died suddenly of dysentery while on a pastoral visit to Asaba.
Worthy of note is that Iyi-Enu Mission Hospital is divinely instituted upon the Rock (Jesus Christ), hence the Lord has been so gracious in spite of the numerous challenges that have been encountered.As At the period under review, Patience that were accessing healthcare services at Iyi-Enu Mission Hospital Came all the way from Ogidi, Nkpor, Oze, Umuoji, Obosi, Awka,Nnewi,Nsukka, Okigwe, Egbu, Ida, among others.
The hospital also embarked on the training of local staff and in 1930-1931, Iyi-Enu school of nursing and Midwifery started in earnest after obtaining approval from the government.