I've been talking a lot about ketosis on my steemit blog. Some of the posts have dealt with the science behind it, while others were simply videos in which I answered to questions related to ketosis.
My recent adherence to the ketogenic diet has increased my interest on the research side of it.
For those who do not know, ketosis is the metabolic state where your body switches its primary fuel substrate from glucose to fat and fat derived products, which are ketones.
Ketones replace sugar metabolism across many tissues and cells in the body, one the most important switch being probably in the brain, where from a glucose dependent brain it turns to using ketones in a proportion of 60 to 75%, while the rest is being provided by glucose (from gluconeogenesis) and other substrates.
To reach ketosis one has to drastically restrict dietary carbohydrate, to less than 50 grams (total carbs) per day or even less. And there are a lot of implications to this...
I'm still very very surprised that outside of a narrow research circle, ketosis and ketogenic diets have an inappropriate 'rap' and that there is a lot of misunderstanding about it, primarily because most people dismiss it using the simplistic and dangerous rationales, such as that it's a high-fat unbalanced diet - which can, in all truth be, without an appropriate and careful approach.
Moreover, given the current pace of the world, the state of ketosis is pretty much unsustainable by most people as you need to be extremely carefully with your carbohydrate intake and cheap, low-quality sources of carbs are everywhere.
I will write much more about ketosis in posts to come, but until then, I'd rather suggest a very good read (somewhat technical) by Peter Attia M.D., himself a practitioner of the ketogenic diet for a long time (now, on a low carb diet).
In his posts Attia discusses about:
- a definition of ketosis and the three ketone bodies
- how the brain switches from glucose to ketones and how it uses them for fuel
- what happens within the Krebs Cycle
- the process of ketogenesis
- the forever existing misunderstanding of the different between ketosis and diabetic ketoacidosis
This is a multi-part series of posts, so you can start with the first one by following the link below:
Indepth Explanation of the Physiologic State of Ketosis - [via Peter Attia]
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Cristi Vlad Self-Experimenter and Author