That need to meet demand for an ever increasing population results in some bad stuff sometimes ( ya know like pesticides as you were talking about) but it's choices of what tradeoffs are worth it and what aren't. I think these chemicals need to be a last resort and new methodologies found to improve agricultural practices but I also probably have a very biased opinion because I spent a summer spraying herbicides and the exposure even with ppe noticably reduced my immune system and I started getting sick all the time. I still have yet to fully recover and get sick much easier than I ever use to.
RE: Poisoning by pesticides is a risk for both agricultural workers and their families and the population in general.