The result of a study conducted in India on the relationship between diabetes and infertility.
According to findings of a study by Jaslok Hospital and Research Centre in Mumbai, diabetes increases the risk of DNA damage in sperms, resulting in infertility. The study which has found that DNA damage among diabetics is more than double as compared to those who are non-diabetics also showed that sperm count is significantly reduced and the movement and appearance of sperm is affected by diabetes.
India is the diabetes capital of the world. Every fifth Indian is estimated to be a diabetic and it’s alarming that increasing numbers of diabetics are seeking infertility treatments.
This finding is therefore true and authentic.
Diabetic men were nearly three times more likely to suffer from sperm apoptosis (break-up of the DNA) than non-diabetics. Higher miscarriage rates in couples may also be seen due to fragmented or broken DNA. ‘It is known that diabetic men may take a longer time to bring about conception in their wives who may also be prone to a higher incidence of miscarriage,’ said Dr Firuza Parikh, director, department of assisted reproduction and genetics, Jaslok Hospital.
The study, which was presented at a seminar on Male Infertility conducted by the centre last week, has found that in diabetes the DNA of the sperm is damaged due to oxidative stress which releases cell death accelerating ions in the body.
The sperm count, motility and morphology (sperm structure) of 60 diabetics and 78 non-diabetics in the age group of 25 to 45 years were studied by Dr Parikh and his team at the assisted reproduction and genetics department. According to Dr Prochi Madon, head, genetics lab at the centre, all these men were newly-diagnosed diabetics who had come to the clinic for infertility treatment. The study which was initiated three years ago found that DNA damage in the diabetic group was 15.9% as compared to 6.4% among the non-diabetic group.
The study also found that in diabetics the sperm’s motility was 22% as against 46% in healthy individuals. Also, the sperm count in diabetic men was less than half of that of the healthy group. 92% of the diabetic men had abnormal sperm structure as opposed to 11% of the normal group.
With this revelation, it's important that individuals who have challenges with fertility should also carry out Fasting Blood Sugar test so as to be doubly sure that they don't have diabetes.
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