I really only see two ways of heavily manipulating crypto:
Massive rumour spreading through the globalist central banker mass-media.
Excessive buying- or selling in a very short period of time.
The first, we really can't do much about, except just ignore the liars. We know who they really serve and why they do, what they do, so fuck the Rhodes roundtable sock puppets.
The second can be stopped if daily, weekly or monthly transactional limitations are in place on all exchanges. Only problem here might be "deep state exchanges" who gain enough market share to impact a crypto's price on the macro scale and who logically don't operate with transactional limitations to enable the manipulation.
How do we handle protecting the crypto space from scenario two? How about an Exchange NGO of which a crypto exchange must be a member and follow certain rules to be licensed for doing business in crypto world? We can't make it happen through state as the dark side owns the state, so we have to come up with something contractual ourselves. Would it be possible to block a non-compliant exchange from the blockchains? Is the answer perhaps to use some kind of "guardian AI" in the blockchain system itself.
How do we handle question two?