Many different views on the matter...

If one was aiming to connect with an audience, at say 200, they’d probably “fail” if banging out at 500. But then again, why would any artist want to lower themselves and sacrifice the integrity of their work?

Whatever flows out is moreless an extraction of their level of consciousness - not even possible to be deliberately lowered or raised significantly. If creating authentically, the vibe’ll be what it’s at - and thus, perhaps setting the base frequency to attract the audience who’s at the same level or prepped to be lifted up to it.

And of course, “best” response is subjective. Music put out will have what effect it will, which is a millions different things to millions of different people. I dunno how much an artist could even try consciously focus his vibe into a particular sweet spot to please an audience, so much as simply remaining true to their own work and letting it do its work...