There are a few plants that have plenty of medicinal benefits and relatively low or virtually none risks associated with their use. One of them is marijuana. Another one is kratom.
Kratom has been used by human for centuries and it help people with insomnia, anxiety, depression, low energy and many more things, depending on the strain.
If you wanna known more about it, here'sa great article where the author goes in depth about it, enjoy!
http://www.psychedelicheaven.com/2017/07/29/everything-you-need-to-know-about-kratom/