Absolutely! I recently realized a fun argument stemming from these sections of Meditations. If the only thing I can know with absolute certainty is my own existence, and that is a subjective experience, then should we really discount subjective experience as being less descriptive of truth than objective experiences?
Senses fail and dreams can seem real. Hell, we don't even sense the actual thing. As Descartes said, “(when I) see men crossing the square … I normally say that I see the men themselves … Yet do I see any more than hats and coats which could conceal automatons? I judge that they are men.” That is, our minds filter our senses based on past experiences. We cannot trust our senses because all previous experiences could be false (eg., pre-programmed, or experienced only within a simulation).
RE: Decartes' Substance Dualism