These will be the people to fight the evolution and advancement of our species. Claiming the work of the devil, and urging us to stick to the ways of our forefathers. The ones that would choose to use an automobile over a horse and buggy, but will not want to embrace the digital manipulation and recapitulation of our consciousness into some massive hive mind, or otherwise.
I'm not going to make the claim that one is any better over the other. I'm fully of the mind that my spirit dwells within me, but is there truly a potential to damage ones self when you are able to operate under an extension of your own self? Would not the machine be a part of that extension? Are our creations also not an expression of the self?
Naturally, an AI would be capable of expanding beyond some of our understandings in an unquantifiable amount of time, but at its nature it would still be an expression of ourselves. But, I'm not really a fan of the idea that we would be indentured by our own creation. Let's see what transpires.
photo credit: http://richardbernard.blogspot.ca/2007/03/puritans.html