Valis III was originally released for the PC Engine CD-ROM2 (TurboGrafx-CD) in 1990 and then for the Mega Drive (Sega Genesis) in 1991. In North America, that release order was reversed for some reason. The Genesis version came out in 1991 while the TurboGrafx-CD version came out in 1992.
Valis III is a side-scrolling adventure game in which the player can switch between several characters. Since the Genesis version was not CD based like the TurboGrafx-CD version, certain compromises were made. Most of the cut scenes were removed from the Genesis version and several levels were removed (though one new level was added). Both versions are well regarded but the TurboGrafx-CD version is a little better because of the differences mentioned.
You can see the box art for both the Japanese and North American releases of the Sega Genesis version of the game above. I'm not sure why they changed the anime style art to what seems to me to be far more generic artwork for the North American Release. Artwork aside, this is definitely a game you should add to your collection if you have either a Genesis or TurboGrafx-CD.
Read more: https://www.megalextoria.com/wordpress/index.php/2017/09/15/valis-iii-sega-genesis/