My background is in physics. A standard tactic, in physics, when faced with extremely complicated problems is to make simplifying assumptions. Simplifying assumptions are very useful to determine whats reasonable and whats not. We see that life is here on earth and some postulate that it is here through a process of random mutations where the non-beneficial mutations are selected out. So the first thing that needs to be done is to see if this postulate is reasonable. If the postulate is not reasonable a lot of time and resources would be wasted going down a dead end research path. The above calculation is done with simplifying assumptions that over estimate the probability that life is here by chance. So what we can conclude is that; life is NOT here through a process of random mutations where the non-beneficial mutations are selected out.
Now where do we go? Like it or not there is only one direction to go. Life is here because it has to be here and life is the way it is because it has to be the way it is. We are forced down a deterministic road.
There is evidence that cells must avoid mutations and repair DNA and or RNA. This is the direction that life extension research is going.
Is there evidence that the development of life is catalyzed? Yes there is.
RE: Speciation of Humans Colonizing Mars