By a News Reporter-Staff News Editor at Women’s Health Weekly -- Investigators publish new report on Oncology - Endometrial Cancer. According to news originating from Rochester, Minnesota, by NewsRx correspondents, research stated, “To assess how the widespread adoption of minimally invasive surgery in the United States is associated with changes in 30-day morbidity and mortality in endometrial cancer treatment. In this retrospective cohort study, the American College of Surgeons’ National Surgical Quality Improvement Project database for 2008-2014 was reviewed for patients who had undergone surgery for endometrial cancer according to their primary Current Procedural Terminology (CPT) codes.”
Our news journalists obtained a quote from the research from Mayo Clinic, “Women with CPT codes for advanced cancer or with disseminated disease were excluded. A trend analysis across the time period by surgical approach (open surgery through laparotomy, vaginal surgery, and minimally invasive surgery) was performed using a Cochran-Armitage test for trend. Thirty-day surgical outcomes were compared between patients who had minimally invasive surgery and open surgery. Inverse probability of treatment weighting models were used to investigate the independent effect of minimally invasive surgery on 30-day outcomes. Overall, 12,283 patients met the inclusion criteria. A significant implementation of minimally invasive surgery (24.2-71.4%) and a concomitant decrease in open surgery through laparotomy (71.1-26.4%) were observed from 2008 to 2014 (both P<.001). Rate of vaginal surgery did not change over time (1.5-2.2%, P=.06). After adjusting for possible confounders, open surgery (compared with minimally invasive surgery) was independently associated with increased odds of major complications (n=347 versus n=274, adjusted odds ratio [OR] 2.4, 95% CI 2.0-2.8), readmission (n=269 versus n=238, adjusted OR 2.2, 95% CI 1.8-2.6), reoperation (n=80 versus n593, adjusted OR 1.5, 95% CI 1.2-2.1), superficial surgical site infection (n=190 versus n=55, adjusted OR 6.8, 95% CI 5.0-9.2), perioperative transfusion (n=430 versus n=149, adjusted OR 5.9, 95% CI 4.8-7.1), and death (n=41 vs, n=20, adjusted OR 3.8, 95% CI 2.2-6.6). A comprehensive decrease in 30-day morbidity for the treatment of endometrial cancer overall was observed from 2008 to 2014 (P <.001), whereas 30-daymortality remained stable (P=.24).”
According to the news editors, the research concluded: “The widespread adoption of minimally invasive surgery is associated with substantial decreases in 30-day morbidity, readmission, and reoperation for women treated for endometrial cancer in the United States.”
For more information on this research see: Adoption of Minimally Invasive Surgery and Decrease in Surgical Morbidity for Endometrial Cancer Treatment in the United States. Obstetrics and Gynecology , 2018;131(2):304-311. Obstetrics and Gynecology can be contacted at: Lippincott Williams & Wilkins, Two Commerce Sq, 2001 Market St, Philadelphia, PA 19103, USA. (Lippincott Williams and Wilkins - www.lww.com; Obstetrics and Gynecology - http://journals.lww.com/greenjournal/pages/default.aspx)
The news correspondents report that additional information may be obtained from A. Mariani, Mayo Clinic, Div Gynecol Surg, Rochester, MN 55905, United States. Additional authors for this research include F. Multinu, D.S. Ubl, S.C. Dowdy, W.A. Cliby, G.E. Glaser, K.A. Butler, F. Ghezzi, E.B. Habermann and J. Casarin.
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2018, NewsRx LLC
CITATION: (2018-05-03), New Findings from Mayo Clinic in Endometrial Cancer Provides New Insights (Adoption of Minimally Invasive Surgery and Decrease in Surgical Morbidity for Endometrial Cancer Treatment in the United States), Women’s Health Weekly, 205, ISSN: 1532-4729, BUTTER® ID: 015569082
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