An important finding related to toxoplasmic encephalitis seen in animals and the schizophrenia that caused it was found. The study has given new insights into the treatment of diseases. Scientific research on animals with chronic toxoplasmosis model showed that for the first time in the world, a significant increase in inflammation-inducing cytokinin (GMF-B) was observed in brain tissues of these animals. Such a finding is the first time in the world that Aksaray University Faculty Member Assist. Assoc. Dr. Güngör was presented by Contemporary Dinçel. Dr. Dinçel said that GMF-B will lead to new perspectives in toxoplasmic encephalitis and schizophrenia treatments caused by it, and that Toxoplasma gondii is a very dangerous protozoan parasite.
The disease is very important for both humans and animals. The parasite, the last host of pets and wild cats, has the ability to infect humans and many animal species. It also causes serious economic loss for our country in terms of animal husbandry. So it is a parasite that needs to be investigated in terms of both importance. In general, humans and animals are caught up with disease as a result of consuming contaminated oocysts with contaminating foods, or meat containing cysts as raw or undercooked. Congenital toxoplasmosis occurs as a result of pregnant women getting infected. The agent can infect the fetus through placenta. It has been observed that the severity of Toxoplasma gondii is further increased in cases such as AIDS, organ transplantation, and the use of immunosuppressive drugs. The most important finding in the study is the establishment of a previously unidentified connection between T. gondii and schizophrenia. When all these findings are taken into consideration and assessed together, it is thought that GMF expressions play an important role in the pathogenesis of schizophrenia caused by T. gondii. In short, cytokine-mediated neuronal injury is thought to contribute to the pathophysiology of schizophrenia by reducing the number and density of neurons.
