Platelet Rich Plasma is defined as a volume of plasma that contains a concentration of platelets higher than the basal plasma level (150,000-450,000/µL), which is achieved through procedures that range from the extraction of blood from the same patient to the application of techniques that allow the activation of platelets, achieving that their content is released by a process of exocytosis through the formation of vesicles that, when in contact with the cellular matrix, allow the release of growth factors (GF) and proteins contained in the granules alpha of platelets, these FC are polypeptides that regulate mitogenesis, chemotaxis, cell differentiation and have multiple regenerative properties that intervene in cellular functions by accelerating the process of tissue repair.
Among the greatest virtues of PRP are its autologous nature since the plasma is extracted from the same patient without risk of rejection, which guarantees its innocuousness, safety, effectiveness and easy handling without the need for surgery.
Some of the diseases in which it has shown significant improvement are:
Arthrosis or Osteoarthritis (OA) which, as you know, is a chronic degenerative disease, causing significant disability and dependency, which generates a high percentage of medical rest by workers affected by these pathologies in companies. As therapeutic treatments for OA, drugs used orally are used, such as non-steroidal anti-inflammatory drugs, injections with glucocorticoids for the treatment of acute exacerbations of pain, among others. These treatments generally have a limited effect over time and are associated with the possible appearance of adverse effects such as gastrointestinal symptoms, hepatotoxicity and nephrotoxicity. Other treatments used are surgeries in which the doctor seeks through the operation to realign the joint and reduce the loads on the internal compartment to relieve pain.
The limited self-regeneration capacity of cartilage and the limitations of current medical treatments for OA place regenerative treatments with PRP as an alternative capable of regenerating injured tissues and consequently improve the quality of life of people with OA. and thus reduce the need to resort to surgical procedures in these patients.
It is also used in:
Odontology.
Neurosurgery: Spine stabilization, craniotomies, fistula prophylaxis, among others.
Dermatology: Skin biostimulation, Alopecia, Acne, Anti-aging treatments, Post Laser, Post Peelings, Cellulite, Fillers.
Reconstructive and aesthetic plastic surgery: Lipectomies.
Cardiovascular Surgery: vessel sealing, Dacron tube procedures, vascular implants, etc.
General surgery: in areas that are estimated to bleed in layer.