Velpanat – Indian generic Epclusa (Sofosbuvir and Velpatasvir) from Natco pharmaceutical company LTD.
Velpanat generic hepatitis medicine is manufactured by Natco Pharma Limited, who is the brand leaders of other hepatitis drugs like Hepcinat , Natdac, Hepcinat LP for the different type of genotypes. Velpanat is an oral fixed-dose combination of Sofosbuvir 400mg, a nucleotide analog NS5B polymerase inhibitor and Velapatasvir 100mg, an NS5A replication complex inhibitor. This fixed dose regimen is a once-daily FDA approved pan-genotypic regimen for the treatment of chronic hepatitis C (HCV) with or without cirrhosis. Addition of ribavirin is recommended for patients with decompensated cirrhosis (CTP B or C).
Generic Epclusa or Velpanat is generally well tolerated, with low rates of adverse events, and low discontinuation rates. Patients with chronic hepatitis C virus infection (HCV) achieved SVR> 95% (SVR) after 12 weeks of treatment with a combination of a direct action antiviral agent (DAA) Sofosbuvir & Velpatasvir.
Important points regarding Velpanat (Sofosbuvir / Velpatasvir) Tablets
Doctor consultation
Discuss with your doctor the following points. Before taking this medicine tell to doctor if you have any of these problems -
• Hepatitis B past history
• HIV
• Kidney disease
• If the patient is pregnant
• If the patient is breastfeeding.
Dosage for Velpanat
Take this medicine in the dose and duration as advised by your doctor. Velpanat 400mg/100mg Tablet may be taken with or without food, but it is better to take it at a fixed time. Swallow it as a whole. Do not chew, crush or break it. Don’t take a tablet for smaller or larger quantities or for the longer duration than recommended by your doctor. Take the medicine on daily basis at the same time.
After taking medicine if you have any allergies you should consult the doctor immediately. The doctor will diagnose the patient.
Velpanat should not be used with certain other medications (including amiodarone, rifampin, St. John’s wort and carbamazepine) due to the risk of drug-drug interactions that could cause side-effects or reduce drug concentrations.
What about Velpanat cost ?
Growing population and an increase in the awareness among the population across the world has resulted in the growth of the Hepatitis C treatment at a significant rate. But, the high cost of Velpanat Velpatasvir Sofosbuvir tablets has become a major concern in several countries, forcing as many as one in four people to go without their medicines. Cutting their pills in half or skipping drug treatment entirely may be harmful for patients.
Unfortunately, the effects of burdensome out-of-pocket costs are not limited to the health of individual patients. When patients are forced to abandon their prescriptions, it can lead to increased health care costs to the system, in the form of unnecessary hospitalizations, emergency services, and physician visits.
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SOURCE : https://chronicmedicines.wordpress.com/2018/04/11/natco-velpanat-velpatasvir-sofosbuvir-tablets/