One way to profit off of a recession would be to purchase an ETF that shorts the market, otherwise known as inverse ETF. Basically, you are betting that the market will go down. My favorite one, SQQQ,

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I'm recently very bullish on NEO. They're down quite a bit from their previous highs. Also, we have word that they will be moving outside of China and going global. They also have a few ICOs and competitions