You need to ask this in more spesific ways. If you asking based on languange or words then i can give you this short kind of answer :

the word “home” comes from the Old English word “ham” which means “dwelling, estate,” or “village.” It is derived from the Proto-Germanic words “haimaz” and “heim” which mean “home.”
The word “house,” on the other hand, comes from the Old English word “hus” which means “dwelling” or “shelter.” It is derived from the Proto-Germanic word “husan” which is connected to the root word of the word “hide.”

And if you asking based of the "define" the different betwen house and home, then i'll give you this :

A home is defined as a place of refuge, a place where one resides and rests after a day of hard work. It is where a family lives and which offers them security, a haven where they can feel at ease, comfortable, and happy. It is where an individual’s most-cherished possessions are kept; where no one can touch them without his permission. It is a place where he can do whatever pleases him away from the prying eyes of other people.
A house is defined as the structure which serves as a dwelling for a person or a family. It is used synonymously with the word “home,” but it usually only refers to the building or structure and not on the overall condition of the place and its inhabitants. It may contain an individual’s personal things or property and provide him with a place to live and rest, but it does not offer the same comfort that one feels when he is home. It can sometimes denote something temporary such as a sorority or fraternity house.

Hope this short of answer can help you tho