I really like the mental exercise of the the "what if" scenario. I think some questions I would probably have would be:

What would it like to be human? Will that in itself be redefined?

What will the family structure look like? Will the world be subject to one culture or will there still be any diversity left?

Will man still be on earth? Will man have a greater presence, perhaps even colonization and exploration, in space?

I think you have some good thoughts. You think about some of the reasons why people even are Christians. For instance, many are brought up in Christian homes. Will that even be a thing? People turn to Jesus in desperation and need, but when you take certain needs out of the equation, do they still turn to him?

I also consider how our emotions play a role in our longing and breaking, and when you physically and chemically alter the body in a way where it's not able to have natural processes of emotion, then where does that leave one in their own pursuit of God?

I'm very interested to see more of these musings and where it takes you!