This article is a prospective randomized trial of patients with chronic kidney disease (CKD) who were assigned to receive allopurinol or not. This study shows that the patients who received allopurinol had slower progression of CKD.
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To quote this article in bibliography:
Goicoechea, Marian, Soledad García de Vinuesa, Ursula Verdalles, Caridad Ruiz-Caro, Jara Ampuero, Abraham Rincón, David Arroyo and José Luño. “Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk." Clinical Journal of the American Society of Nephrology 5, no. 8 (2010): 1388-1393. doi: https://doi.org/10.2215/CJN.01580210
