This article is a prospective randomized trial of patients with chronic kidney disease (CKD) who were assigned to receive allopurinol or not. This study shows that the patients who received allopurinol

Allopurinol hypersensitivity syndrome typically occurs in persons with preexisting kidney failure.[1]:119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption[1]:119